Product name: Tramadol

Active substance: Tramadol Hydrochloride

Brand names: Ultram

Dosage Strength(s): 50MG, 100MG

Quantity: 90 – 2000 Tablets

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Product Description

Tramadol is a prescription medication used to treat moderate to severe pain in adults. It is classified as an opioid analgesic and is available in both immediate-release and extended-release formulations. Tramadol is often prescribed when other pain relievers, such as acetaminophen or ibuprofen, have not provided adequate relief.

Mechanism of Action:

Tramadol works by binding to specific receptors in the brain and spinal cord, which reduces the perception of pain. In addition to its pain-relieving effects, tramadol also increases the levels of certain neurotransmitters, including serotonin and norepinephrine, which can help improve mood and provide a sense of well-being.


Tramadol is not suitable for everyone. It should not be used by individuals who are allergic to tramadol or any of its components. It should also be avoided in patients who are experiencing respiratory depression, as tramadol can further depress breathing.

Tramadol should be used with caution in patients who have a history of seizures, as it may lower the seizure threshold. It should also be avoided in patients who are taking monoamine oxidase inhibitors (MAOIs), as the combination can lead to serotonin syndrome, a potentially life-threatening condition.

Side Effects:

Like all medications, tramadol can cause side effects. The most common side effects include:

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Constipation
  • Drowsiness
  • Dry mouth
  • Sweating

In rare cases, tramadol can cause more serious side effects, such as:

  • Seizures
  • Respiratory depression
  • Serotonin syndrome
  • Allergic reactions, including anaphylaxis

Drug Interactions:

Tramadol can interact with other medications, including:

  • Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs), which can increase the risk of serotonin syndrome.
  • Benzodiazepines and other sedatives, which can increase the risk of respiratory depression and other side effects.
  • Warfarin and other blood thinners, which can increase the risk of bleeding.

It is important to inform your healthcare provider of all medications you are taking before starting tramadol.

Method of Usage:

Tramadol is available in immediate-release tablets, extended-release tablets, and capsules. The immediate-release tablets are typically taken every four to six hours as needed for pain, while the extended-release tablets and capsules are taken once or twice a day.

Tramadol should be taken with food or milk to help prevent stomach upset. It should also be taken exactly as prescribed, and never taken in larger doses or for longer than prescribed.

Additional Information:

Tramadol has the potential for abuse and addiction, particularly in individuals with a history of substance abuse or addiction. It is classified as a Schedule IV controlled substance by the United States Drug Enforcement Administration (DEA).

Tramadol should not be abruptly discontinued, as this can lead to withdrawal symptoms, including anxiety, sweating, nausea, and insomnia. It is important to gradually taper off the medication under the guidance of a healthcare provider.


In conclusion, tramadol is an opioid analgesic used to treat moderate to severe pain. It works by binding to specific receptors in the brain and spinal cord, and can increase the levels of certain neurotransmitters to improve mood. Tramadol has potential side effects, drug interactions, and contraindications, and should be used with caution in patients with certain medical conditions or who are taking certain medications. It should be taken exactly as prescribed, and individuals should be monitored for signs of abuse or addiction.


While every effort has been taken to ensure that the information provided is accurate, up-to-date and complete, Prime Medical Pharma cannot guarantee its accuracy. Please note that the drug information contained herein may be time-sensitive and should not be relied upon beyond the date hereof. This material is intended as a reference resource and should not be used as a substitute for the expertise, skill, knowledge, and judgment of healthcare practitioners in patient care. It is important to note that the absence of a warning for a given drug or combination thereof does not imply safety, effectiveness, or appropriateness for any particular patient. This material does not endorse drugs, diagnose patients, or recommend therapy.



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