Product name: Zolpimist Oral Spray
Generic Name: Zolpidem oral spray, metered
Brand Names: Ambien, Ambien CR, Edluar, Intermezzo
Dosage Strength: 5mg/0.1mL Spray
Quantity: 30 mL bottle

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Zolpimist (zolpidem oral spray) is a sedative, also called a hypnotic. It affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia).

Zolpimist oral spray is used in adults for the short-term treatment of a sleep problem called insomnia (trouble falling asleep).

Zolpimist is used to help you fall asleep


Usual Adult Dose for Insomnia:

Initial Dose: 5 mg (women) OR 5 mg or 10 mg (men)

Maintenance Dose: The dose may be increased to 10 mg if the 5 mg dose is not effective.

Maximum Dose: 10 mg once a day.

Duration of Therapy: The clinical trials in support of efficacy were 4 to 5 weeks in duration.

Comments: The recommended initial doses for women and men are different due to the lower rate of drug clearance in females.

Use: Short-term treatment of insomnia characterized by difficulties with sleep initiation.

Usual Geriatric Dose for Insomnia:

Men and women: 5 mg.


Zolpidem may cause a severe allergic reaction. Stop using Zolpimist and get emergency medical help if you have signs of an allergic reaction to zolpidem: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: depression, anxiety, aggression, agitation, confusion, unusual thoughts, hallucinations, memory problems, changes in personality, risk-taking behavior, decreased inhibitions, no fear of danger, or thoughts of suicide or hurting yourself.

Stop using Zolpimist and call your doctor at once if you have:

chest pain, fast or irregular heartbeat, feeling short of breath;

trouble breathing or swallowing; or

feeling like you might pass out.

The sedative effect of zolpidem may be stronger in older adults.

Dizziness or severe drowsiness can cause falls, accidents, or severe injuries.

Common Zolpimist side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

What other drugs will affect Zolpimist?

Using Zolpimist with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Many drugs can interact with zolpidem, making it less effective or increasing side effects. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.


While every effort has been taken to ensure that the information provided is accurate, up-to-date and complete, Prime Medical Pharma cannot guarantee its accuracy. Please note that the drug information contained herein may be time-sensitive and should not be relied upon beyond the date hereof. This material is intended as a reference resource and should not be used as a substitute for the expertise, skill, knowledge, and judgment of healthcare practitioners in patient care. It is important to note that the absence of a warning for a given drug or combination thereof does not imply safety, effectiveness, or appropriateness for any particular patient. This material does not endorse drugs, diagnose patients, or recommend therapy.

Additional information

0.433 kg


91 × 157 × 122 cm



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